Eclipta Alba Extract
Botanical Source: Eclipta prostrata L.
Specifications: Wedelolactone 2%,4.5% by HPLC
CAS No.:524-12-9
Appearance: Brownish yellow powder
Main Ingredients:
Ecliptae contain nicotine is about 0.08% saponins, 1.32%, tannic acid, vitamin A, Li intestine element (Ecliptine), A variety of thiophene compounds such as alpha sanlian thiophene base methanol (alpha Terthienylmethanol) and its acetate, etc. Leaves contain identify chrysanthemum lactone (Wedelolactone), methyl identify chrysanthemum lactone (Demethylwedelolactone), to identify chrysanthemum lactone - 7 - glucose glucoside.
Pharmacological Effects:
1. The hemostatic effect according to the report, the femoral artery to cut off the dog, with a dry lotus of grass powder, apply the hemorrhage and oppress slightly, with good hemostatic effect. In addition, the dry lotus grass also have elevated the role of peripheral white blood cells, white blood cells reduce disease can reduce caused by cyclophosphamide.
2. The experiment showed that the function of the liver in advance to the ink dry lotus extract female Guinea pigs for carbon tetrachloride induced acute liver injury has obvious protective effect. 24 hours to medicine group animal mortality (22.2%), significantly lower than the control group (77.7%). Dosage groups of animal serum aspartate transaminase, serum alanine aminotransferase and alkaline phosphatase activity decreased significantly; Lobular central necrosis of liver parenchyma cell degeneration, water and fatty degeneration was also significantly reduce.
3. Dry lotus grass has the function of cardiovascular system to increase the role of Guinea pigs in vitro heart coronary flow, make the electrocardiogram T wave is improved. The injection of dry lotus grass can make the normal pressure hypoxia circumstances of mice significantly prolong life, also can improve the survival rate of mice under the environment of decompression and lack of oxygen. Dry lotus grass dilate coronary blood vessels and increase coronary artery flow and increase the role of hypoxia ability fast, long time, and low toxicity.
4. Other function experiments show: The dry lotus grass can improve the survival rate of mice decompression hypoxia circumstances; Can significantly extend the life of the normal pressure hypoxia circumstances in mice. Dry lotus grass in mice sedation and analgesia effect is very significant.
Wedelolactone:
Synonym(s): 7-methoxy-5,11,12-trihydroxycoumestan
CAS Registry Number:524-12-9
Molecular Formula & weight: C16H10O7; 314.3
Accurate Mass:314.2464 g/mol
Physical Description: Fine brownish yellow powder
Boiling Point: 498.4 ºC at 760 mmHg
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