Liver Health Natural Silymarin Silybin Isosilybin Milk Thistle Extract

• Customization: Available
• Certification: ISO, HACCP, Kosher, Halal
• Assay Method: HPLC-MS
• Model NO.: Silymarin 80% with Silybin, isosilybin 30%
• Application Form: Tablet, Capsule
• Application: Health Care Products, Medicine
• State: Powder
• Extract Source: Valerian Root
• Botanical Source: Silybum Marianum (L.) Gaertn
• Plant Part Used: Seed,100% Natural
• Appearance: Fine Yellowish Brown Powder
• Assay: Silymarin 80% with Silybin, Isosilybin 30%
• Loss on Drying: Nmt 5.0%
• Ash Content: Nmt 5.0%
• Extract Solvents: Ethanol & Water
• Solvent Residues: Nmt 0.05%
• Heavy Metals: Nmt 10ppm
• Arsenic (as): Nmt 1ppm
• Lead (Pb): Nmt 2ppm
• Cadmium (CD): Nmt 1ppm
• Mercury(Hg): Nmt 0.1ppm
• Total Plate Count: <1000cfu/G
• Total Yeast & Mold: <100cfu/G
• Transport Package: 25kg/Drum
• Specification: Silymarin 80% with Silybin, isosilybin 30%
• Trademark: Kingherbs
• Origin: Yongzhou, China
• HS Code: 2938909090
• Production Capacity: 100, 000kg

Product Description

Milk Thistle Extract

Product Name: Milk Thistle Extract
Botanical Source: Silybum marianum (L.)Gaertn
Plant Part Used: Seed
Specification: Silymarin 80% by UV, Silybin 30% HPLC; Silymarin 80% by UV, Silybin+Isosilybin 30% by HPLC
CAS No.: 22888-70-6
Molecular Formulation: C25H22O10
Molecular Weight: 482.43
 

Analysis Items		Specifications
Appearance		Fine Yellowish Brown Powder
Odor & Taste		Characteristic
Bulk Density		50-60g/100ml
Particle Size		NLT 95% through 80 Mesh
Solubility		Practically insoluble in water, soluble in Methanol & acetone
Assay		NLT 80% silymarin
		Silymarin
		Sum of silycristin and silydianin
		Sum of silybin А and silybin В
		Sum of isosilybin А and isosilybin В
Loss on Drying		NMT 5.0%
Sulphated Ash		NMT 0.5%
Extract Solvents & Residue		Acetone NMT 5000ppm
		Ethanol  NMT 5000ppm
		N-hexane  NMT 290ppm

 
Indications:
Milk thistle's common name comes from the white markings on the leaves, its milky white sap, and its traditional use by nursing mothers to increase milk. But it is best known for its use as a liver protectant and decongestant, which can be traced to the Greeks and Pliny the Elder (23-79AD), who wrote that it was excellent for "carrying off bile." The famous English herbalist Culpepper (1616-1654) used milk thistle to cleanse the liver and spleen, and to treat jaundice and gallstones.

The whole herb contains flavonoids and fumaric acid; Seeds contain silybin, isosilybin, dehydrosilybin, silydianin, silychristin, silybin polymer and cinnamic acid, myristic acid, palmitoleic acid, arachidonic acid, etc. 
1. Liver protection
Silymarin is the main active ingredient of liver protection, which can stimulate the formation of new liver cells and improve liver function. At the same time, it can protect the liver cell membrane, prevent the infiltration of cytotoxin into liver cells, and improve the recovery ability of membrane structure defect.
2. Antioxidant
Silymarin's phenolic hydroxyl group provides hydrogen and has a powerful antioxidant effect. They have the properties of scavenging free radicals and anti-lipid peroxidation activity.
3. Reduce blood lipid
Silybin can inhibit the plasma membrane Ca2+ channel of myocardium in adult rats, inhibit food-induced hypercholesterolemia, decrease very low density lipoprotein (VLDL) and low density lipoprotein (LDL), and increase high density lipoprotein (HDL), which can be used for the treatment of cardiovascular diseases.