100% Natural Cinchona Bark Powder / Extract 4: 1, 10: 1

• Botanical Source: Cinchona Calisaya Wedd.
• Appearance: Fine Brownish Yellow Powder
• Plant Part Used: Bark
• Shelf Life: 2 Years
• Transport Package: Packed in Fiber Drum, LDPE Bag Inside. 25kg/Drum
• Specification: 4: 1, 10: 1
• Model NO.: Powder, 4: 1, 10: 1
• Trademark: kingherbs
• Origin: China
• HS Code: 1302199099
• Production Capacity: 500kgs

Product Description

Description
Chinchona bark is best known as the source of the anti-malarial drug and is now cultivated throughout the tropics, including regions of Africa. There are 38 known species in the genus. At least three of these species (C. officinalis, C. ledgeriana, C. succirubra) have a high enough concentration of alkaloids to be cultivated commercially for their medicinal value.
Species of cinchona are all evergreen, with waxy, dark green leaves resembling other species of the Rubiaceae family (such as coffee). They may be shrubs or trees, up to 15 m in height. The flowers are produced in panicles and may be white, red, or pink depending on the species.
 It is the bark of the tree that is used in herbal medicine and is sourced for drugs. The bark is stripped from the tree, dried, and ground into a powder. In the cinchona bark plantations the trees that are stripped regrow some of their bark and are harvested again before they are felled.
In cultivation, it is sometimes a practice to grow moss on the cinchona trees. This seems to increase the concentration of alkaloids in the bark.
The medicinally active compounds in cinchona bark are mostly alkaloids. In addition to the familiar anti-malarial alkaloid there is its stereoisomer quinidine, used in cardiac medicine, as well as other pairs of alkaloids that are useful building blocks in synthetic chemistry: cinchonine and cinchonidine, and dihydroquinidine. Cinchona bark also contains a tannin, cinchonic acid, which is used to perform protein assays in laboratory work.
It is also used as a bitter for food and drink flavoring.
The native Quechua people, living in what is now Peru, had been using the bark of cinchona trees for treating hypothermia and fever and this is what led to its development as a drug for malaria. The Jesuits in colonial Peru, knowing of the local use of cinchona for treating fever, began to use concoctions of the powdered bark to treat malaria patients, beginning in the 1630s.
The active ingredient against malaria, the alkaloid, was isolated in the 1820s, prompting further cultivation of trees, especially C. ledgeriana and C. succirubra. In the 1940s, after the active alkaloid was isolated and identified drug companies were able to develop synthetic. Some strains of malaria have become resistant to the synthetic which has instigated renewed interest in sourcing natural from cinchona.
In treating malaria, the mode of action of cinchona bark may be both antipyretic (anti-fever), and anti-microbial; that is to say that cinchona might be treating the symptoms of the infection, i.e., the fever, while also combating the micro-organism itself. The micro-organism that causes malaria is called a protist and not a virus or bacterium. The mechanisms by which interferes with the protist are becoming more clear with advanced research.
The protozoan parasite Plasmodium falciparum, one of five species of protists that cause malaria in humans, has developed resistance to other malarial drugs, sometimes within a year of the drug being introduced. In contrast, remains effective even today, after centuries of use. The protist's resistance to appears to be only "low-grade", meaning that does retain some delayed or diminished action against it.
The blood and cardiac disorders that have traditionally been treated with this medicinal herb are: anemia, varicose veins and irregular heartbeat (arrhythmia). In the case of arrhythmia there is much laboratory and clinical evidence to support these claims and some prescription medicines for arrhythmia are in fact derived from cinchona.
Cinchona bark has been used as a remedy for heart palpitations (arrhythmia) since at least 1749, when the French physician Jean-Baptiste de Sénac published his observations. This medicine was sometimes called the "opium of the heart". The drug contained in cinchona that has these cardiac effects is quinidine. (Stereoisomers are chemicals that have the same molecular formula but whose structures differ in three-dimensional space and are essentially mirror images of each other.)
It was not until 2010 that British scientists successfully synthesized quinidine in a lab. Until then this prescription drug used to treat arrhythmia was extracted from the plant.
Digestive disorders that are supposedly remedied by the use of cinchona bark are: dyspepsia (stomach upset), anorexia, gastrointestinal disorders, diarrhea, gallbladder disease, and even flatulence. There are few, if any, scientific studies that would either support or refute these claims.
The antiseptic qualities of cinchona bark have been recognized by native people of the Americas for centuries. In modern research, the anti-microbial activity of compounds found in cinchona bark was found to depend on the virus or bacterium in question and the actual compounds. Certainly the alkaloid s an effective treatment against the malaria virus. There is less evidence that cinchona bark is useful as a general anti-microbial agent, i.e., antiseptic.
Although cinchona bark is often cited in the ethnobotanical literature of it anti-bacterial properties, the scientific evidence is mixed. Indian researchers, found that cinchona bark was effective in treating these common bacteria: Staphylococcus aureus, Bacillus cereus, andEscherichia coli but not Streptococcus ß hemolytic and Pseudomonas aeruginosa. The cinchona was effective in killing the yeast Candida albicans.
Biofilms are whole surfaces of micro-organisms (bacteria, yeast cells, or slime) that stick together and undergo cellular changes. They are much more resistant to most available antibiotics and so have attracted the interest of drug researchers. The cinchona alkaloid cinchonidine was tested against Staphylococcus aureusbiofilm and found to be inactive; whereas a synthetic chemical derived from cinchonidine was effective.
It should be noted that anti-biotic drugs, whether natural or synthesized, are highly specific to the particular species and strain of micro-organism. Therefore, no general conclusions can be drawn one way or the other from these handful of studies on whether cinchona is an effective general anti-biotic.
Cinchona bark has been used in traditional herbal medicine to treat muscle spasms. This traditional use of cinchona bark has prompted medical studies. There are a few reports of the successful use of cinchona in treating painful leg cramps and spasms, with only tinnitus as a side effect. The mode of action is unknown, largely because it is not certain what (at the chemical level) causes muscle spasms in the leg. The Journal of Family Practice conducted a review of the literature in 2008 and found that there is no clear evidence that salts are an effective treatment. Most doctors recommend general painkillers to alleviate the symptoms.
Another interesting possibility for cinchona as an herbal remedy is in healthy weight maintenance. Cinchona has been used in traditional medicine as an appetite stimulant. It may also help in weight loss - though not through the suppression of appetite. The possible medicinal value of as a weight control herb was investigated in the 1970s in experiments with rodents but there is renewed interest in cinchona for this purpose. A very recent study (2013) showed that the herb suppressed weight gain without affecting appetite and food consumption in adult male mice. 
The treatment of malaria is certainly what cinchona is best known for. However, there are a number of other health complaints that have been treated with this herbal remedy. Some, but not all, of these conditions have been shown in laboratory and clinical studies to respond favorably to treatment with cinchona compounds.
There are a variety of health problems that have been traditionally treated with cinchona bark. It should be remembered that it is often the case that a medicinal plant containing one or more highly effective compounds is then reputed to cure a host of illnesses and becomes a panacea. Among the list of other maladies purportedly treated by cinchona are: hair loss, alcoholism, hemorrhoids, enlarged spleen and the common cold.
The traditional way of preparing the medicine was to grind the dried bark into a powder, prepare a decoction (boiling the powder) and then either drinking as a bitter tea or mixing with wine or other alcohol.
There are recommended dosages given in several herbalist reference books. It should be stressed that the alkaloids contained in cinchona bark are powerful drugs and therefore no one should self-administer a cinchona decoction without consulting a medical doctor.


Benefit
1 Treating various kinds of liver cancer, breast cancer, mesenteric cancer, and cancer of the other glands and     spleen. Besides this, it is also used for treating amoebic infections, dysentery, dyspepsia, diarrhoea, temperature, lumbago, malaria, pneumonia, sciatica, varicose veins, hangovers and even typhoid.
2 This herb contains analgesic, anaesthetic, antiarrhythmic, anti-bacterial, anti-malarial, anti-microbial, anti-parasitic, anti-pyretic, antiseptic, anti-spasmodic, antiviral, astringent, bactericide, cytotoxic, febrifuge, fungicide, insecticide, nervine, and stomachic therapeutic properties. Cinchona is bitter and works well for reducing fevers and also for back pain. It kills bacteria and also viruses and of course parasites. The liquid extract is useful as a cure for drunkenness. Cinchona extract is also applied to the skin for haemorrhoids, stimulating hair growth, and managing varicose veins.
3 It is used as a tonic and a digestive stimulant for the cure of conditions like indigestion, gastro-intestinal disorders and also as an appetite stimulant. Many people use chaparral as a good throat astringent and its powdered form is often used in tooth powders, because of its astringency.



 

*Herbal Extract
*Herbal oil
*Natural color
*Herbal powder
*Vegetable & Fruit powder
*Softgel
*Vitamin & Mineral
*Pharmaceutical Application
*Food Supplement Application

 

Characteristic
- We can also customize orders as customer's requirements and specifications. 
- KINGHERBS' is specialized in manufacturing and exporting different kinds of food industry related goods, such as Artemisinin, Myricetin, Olive Leaf Extract Oleuropein 10%~80%, Hydroxytyrosol 5%-50%; 
Olive Fruit Extract Maslinic Acid 5%~50% ; Dihydromyricetin, Sea Buckthorn Oil,   Zinger Zerumbet Extract
Fenugreek Seed Extract Furostanol Saponins 50%, Apple Root extract, Rosemary Extract Rosmarinic Acid 2%~98%, Carnosic Acid 5%~80% etc
- With the effective exporting system and prompt reaction, we ensure that we can transfer the shipping documents and deliver our cargoes on time. 

FAQ
Q1. About Price: 
The price is negotiable. It can be changed according to your quantity or package. 
Q2. About Sample: 
We can provide the typical size of samples, but the air freight is collect or you pay us the cost in advance.
Q3. About MOQ:
We have no provisions of MOQ, but usually 1KG.
Q4:About Delivery Time
Usually 5-10 days after payment