Polydatin
Plant Origin: Polygonum Cuspidatum
Part Used: Root
Specification: Polydatin 20%,40%,98% By HPLC
CAS No.: 65914-17-2
Molecular Formula: C20H22O8
Molecular Weight: 390.38
Melting Point: 223ºC~226ºC
Appearance: White or Grey Brownish White Powder
| Analysis Items |
Specifications |
Results |
Methods used |
| Appearance |
Fine Brown Powder |
Conforms |
Visual test |
| Odor & Taste |
Characteristic |
Conforms |
Organoleptic test |
| Loose Density |
NLT 30.0g/100ml |
31.5g/100ml |
USP<616> |
| Tapped Density |
NLT 50.0g/100ml |
51.6g/100ml |
USP<616> |
| Particle Size |
NLT 98% through 80 Mesh |
Conforms |
AOAC 973.03 |
| Solubility |
Soluble in ethanol & water solution |
Conforms |
Visual |
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| Assay |
NLT 50% Resveratrol |
50.16% |
HPLC |
| Emodin |
NMT 2.0% |
1.90% |
HPLC |
| Loss on Drying |
NMT 5.0% |
1.72% |
5g / 105ºC / 2hrs |
| Sulphated Ash |
NMT 5.0% |
0.65% |
2g / 525ºC /3hrs |
| Extract Solvents |
Ethanol & Water |
Conforms |
/ |
| Solvent Residues |
NMT 0.05% |
Conforms |
USP-GC |
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| Heavy Metals |
NMT 10ppm |
Conforms |
ICP-MS |
| Arsenic (As) |
NMT 2ppm |
Conforms |
ICP-MS |
| Lead (Pb) |
NMT 2ppm |
Conforms |
ICP-MS |
| Cadmium (Cd) |
NMT 1ppm |
Conforms |
ICP-MS |
| Mercury(Hg) |
NMT 0.1ppm |
Conforms |
ICP-MS |
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| Sterilization Method |
High temperature & pressure for a short time of 5~10 seconds |
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| Microbiological Data |
Total Plate Count<1,000cfu/g |
Conforms |
GB 4789.2 |
| Total Yeast & Mold<100cfu/g |
Conforms |
GB 4789.15 |
| E. Coli to be negative |
Negative |
GB 4789.3 |
| Staphylococcus to be negative |
Negative |
GB 4789.4 |
| Salmonella to be absent |
Absent |
GB 4789.10 |
Function:
Root of Polygonum cuspidatum is wild, no pesticides or chemical pollution. Polydatin is the glycoside of Resveratrol (sc-200808) originally isolated from the Chinese herb Polygonum cuspidatum. The compound has been shown to inhibit platelet aggregation and elevate the ratios of LDL-C/HDL-C and TC/HDL-C. Myocardial cell, white blood cell, vascular smooth muscle cell, and endothelial cell studies report that Polydatin can inhibit ICAM-1 expression, elevate Ca2+, weaken white blood cell-endothelial cell adhesion, and activate KATP channels.
Polydatin pharmacological functions such as antisepsis, oxidation resistance. Protecting against heart disease, cancer, platelet aggregation, vessel flaccidity, decreasing blood fat and resisting mutagenesis, etc.
1. Antithrombotic effect.
2. Prevent the arteriosclerosis.
3. Prevent and cure the cerebral ischemia.
4. Shrink the contractile cell.
5. Low the whole blood viscosity.
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