Customization: | Available |
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Certification: | ISO |
Assay Method: | HPLC, UV |
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Rutin
Botanical source: Styphnolobium japonicum(L.)
CAS No.: 153-18-4
Molecular formula: C27H30O16
Molecular weight: 610.51
Specification: Rutin 95%UV NF11; Rutin 98%UV EP
Description
Rutin is a bioflavonoid. Pure rutin is yellow or yellow-green colored needle-shaped crystal. Rutin is a flavonol glycoside comprised of the quercetin and the disaccharide rutinose (rhamnose and glucose). Rutin is found in many plants, especially the buckwheat plant fagopyrum esculentum moench, the flour of which is used to make pancakes. Other rich dietary sources of rutin include black tea and apple peels. Many, if not most, of rutin's possible activities can be accounted for, in part, by rutin's antioxidant activity. Rutin is a phenolic antioxidant and has been demonstrated to scavenge superoxide radicals.
Distribution
Rutin is found in many plants, fruits and vegetables. The richest source is buckwheat. Rutin is also found in citrus fruits, noni, black tea, apple peel. During digestion much of the rutin is metabolized to its aglycone, quercetin.
Health Benefits of Rutin
Rutin has strong antioxidant properties. Rutin has also the property to chelate metal ions, such as iron, thereby reducing the Fenton reaction (production damaging oxygen radicals). Rutin also seems to stabilize vitamin C. If rutin is taken together with vitamin C, the activity of ascorbic will be intensified.
Rutin is important because it strengthens capillaries and can help people who bruise or bleed easily. Studies have demonstrated that rutin can help to stop venous edema, that is an early sign of chronic venous disease of the leg.
Rutin has anti-inflammatory effects. Animal studies have shown that rutin has preventive and healing effects.
There are indications that rutin can inhibit some cancerous and pre-cancerous conditions.
Rutin may help to prevent atherogenesis and reduce the cytotoxicity of oxidized LDL-cholesterol
Main functions
Anti-inflammatory ;
Containing Vitamin P, protecting capillaries and prevent bruising;
Reducing the brittleness, dispelling lipids from the fat infiltrated liver;
Keeping the vascular resistance and reduce its permeability;
Antivirus and inhibiting the aldose reductase effects
Application
It used to prevent stroke, hypertension, retinal hemorrhage, purpura, and acute hemorrhagic nephritis. The treatment of chronic bronchitis, efficiency reaches 84.8% and 98%. Troxerutin as its derivatives used in the treatment of burns, arthritis & all kinds of vascular disease, has been the sale of goods abroad. China also produces this drug: The efficiency for cerebrovascular disease 87.8%, cure retinal edema and bleeding 88%.
Analysis Items | Specifications | Results | Methods used |
Identification | A. The specific absorbance at the aximum at 358 nm is 305 to 330,calculated with reference to the anhydrous substance | Conforms | EP8.0 |
B. Spectrogram obtained by the substance to be examined conforms to that obtained by the reference substance | Conforms | EP8.0 | |
C. The principal spot in the chromatogram obtained with the test solution is similar in position,colour and size to the principal spot in the chromatogram obtained with the reference solution | Conforms | EP8.0 | |
D. A red colour develops | Conforms | EP8.0 | |
Appearance | Yellow or greenish-yellow crystalline powder | Conforms | Visual test |
Odor & Taste | Characteristic | Conforms | Organoleptic test |
Bulk density | 45.0~55.0g/100ml | 46.1g/100ml | ASTM D1895B |
Solubility | Soluble in methanol, sparingly soluble in ethanol, practically insoluble in ethylene chloride. It dissolves in solutions of alkali hydroxides. | Conforms | Visual |
Particle size | 99% through 80 mesh | Conforms | AOAC 973.03 |
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