White Peony Extract Paeoniflorin for Skin Care

• Certification: ISO, FDA, HACCP
• Assay Method: HPLC
• Application Form: Tablet, Capsule
• Application: Food, Health Care Products
• State: Powder
• Botanical Source: Paeonia Lactiflora(P.Albiflora)
• Model NO.: CAS 23180-57-6
• Plant Parts Used: Root,100% Natural
• Transport Package: 25kgs/Drum
• Specification: 50%-98% Paeoniflorins
• Origin: China
• HS Code: 1302199099
• Production Capacity: 5000kg

Product Description

White Peony Extract

Specification:10%-98% Paeoniflorin HPLC
Botanical Source: Paeonia Lactiflora(P.albiflora)
Appearance: Fine Brownish Yellow Powder
Extract Solvents: Ethanol & Water 
 

Analysis Items		Specifications	Results		Methods used
Appearance		Fine Brownish Yellow Powder	Conforms		Visual test
Odor & Taste		Characteristic	Conforms		Organoleptic test
Bulk Density		40-55g/100ml	45g/100ml		ASTM D1895B
Particle Size		98% through 80 Mesh sieves	Conforms		AOAC 973.03
Solubility		Soluble in hydro-alcoholic solution	Conforms		Visual
Assay		50% Paeoniflorins	50.08%		HPLC
Loss on Drying		NMT 5.0%	3.62%		USP
Ash Content		NMT 5.0%	3.90%		2g /525ºC /3hrs
Extract Solvents		Ethanol & Water	Conforms		/
Solvent Residues		NMT 0.05%	Conforms		USP-GC
Heavy Metals		NMT 10ppm	Conforms		ICP-MS
Arsenic (As)		NMT 2ppm	Conforms		ICP-MS
Lead (Pb)		NMT 3ppm	Conforms		ICP-MS
Cadmium (Cd)		NMT 1ppm	Conforms		ICP-MS
Mercury(Hg)		NMT 0.1ppm	Conforms		ICP-MS

Introduction:
Paeoniflorin has the effect of relaxing smooth muscle cells, and the reduction of Ca2+ plays an important role in the relaxation of smooth muscle cells of paeoniflorin. Paeoniflorin may relax smooth muscle cells by regulating the exchange of Ca2+/Na+ in the cell membrane. In gastrointestinal smooth muscle cells, the membrane potential determines the contractile and diastolic functions of the gastrointestinal tract by affecting the excitability of the smooth muscle cells. The pharmacological effects of paeoniflorin are mainly to inhibit the excitation of parasympathetic nerves, reduce the tension of smooth muscle and inhibit its movement.
Intravenous injection of paeoniflorin can significantly reduce the blood sugar of streptozotocin-induced diabetic mice, and the blood sugar content in plasma also decreases gradually with the prolongation of administration time. The strongest effect occurred 25 minutes after administration. Paeoniflorin reduces the level of glucose in plasma, and the effect is related to the amount (1 ~ 10mg/kg body weight).