Plant Original: Citrus Aurantium L.
Part Used: Peel of orange
Specification: Hesperidin 95% By HPLC
CAS No.: 520-26-3
Molecular Formula: C28H34O15
Molecular Weight: 610.57
Melting Point: 251ºC
Specific Optical Rotation: -71°~ -79°
Descroption:
Hesperidin is a flavanone glycoside found abundantly in citrus fruits. Its aglycone form is called hesperetin. Its name is derived from the Hesperides nymphs of Greek mythology. Hesperidin is believed to play a role in plant defense. It acts as an antioxidant according to in vitro studies.
Why Do People Use Hesperidin?
Hesperidin is thought to have beneficial effects on blood vessels. It's touted as a natural remedy for a number of health problems, including: allergies, hemorrhoids, high blood pressure, hot flashes, hay fever, sinusitis, symptoms associated with menopausal changes, premenstrual syndrome, and varicose veins.
Funstions:
1. Hesperidins has antioxidant, anti-inflammatory, hypolipidemic, vasoprotective and anticarcinogenic and cholesterol lowering actions.
2. Hesperidins can inhibit following enzymes: Phospholipase A2, lipoxygenase, HMG-CoA reductase and cyclo-oxygenase.
3. Hesperidins improve the health of capillaries by reducing the capillary permeability.
4. Hesperidins are used to reduce hay fever and other allergic conditions by inhibiting the release of histamine from mast cells. The possible anti-cancer activity of hesperidins could be explained by the inhibition of polyamine synthesis.
5. Relieve of cough and asthma.
Possible Side Effects and Safety
Hesperidin may trigger a number of side effects, including abdominal pain, diarrhea, contact dermatitis, and nausea.Hesperidin supplements may not be safe for people taking certain medications (including anticoagulants, blood pressure drugs, and calcium channel blockers). Therefore, it's important to consult your physician if you're considering using hesperidin in combination with other medications. Clinical research suggests that hesperidin may affect blood clotting and increase the risk of bleeding. People taking anticoagulant/antiplatelet medications, those with bleeding disorders, and people two weeks before or after surgery shouldn't take hesperidin.There was a reported case of thrombocytopenic purpura (a disorder that can lead to easy or excessive bleeding or bruising) associated with the use of two supplements containing mainly citrus bioflavonoids.Supplements haven't been tested for safety and due to the fact that dietary supplements are largely unregulated, the content of some products may differ from what is specified on the product label. Also keep in mind that the safety of supplements in pregnant women, nursing mothers, children, and those with medical conditions or who are taking medications has not been established. You can also get tips on using supplements here, but keep in mind that self-treating a condition and avoiding or delaying standard care may have serious consequences.
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