Natural Bearberry Leaf Extract Arbutin

• Certification: ISO, FDA, HACCP, Kosher, Halal
• Assay Method: HPLC
• Application Form: Suppository, Paste, Tablet, Capsule
• Application: Health Care Products, Medicine
• State: Powder
• Botanical Source: Vaccinium Macrocarpon L
• Model NO.: 497-76-7
• CAS No: 497-76-7
• Specifications: 99% Arbutin
• Appearance: Fine White Powder or Crystalline Powder
• Plant Part Used: Dried Leaf
• Transport Package: PA⪞ Ked in Bag. Net Weight: 1kg/Bag.
• Specification: 99% Alpha Arbutin
• Trademark: Kingherbs
• Origin: Yongzhou of Hunan Provin⪞ E
• HS Code: 29389090
• Production Capacity: 5000kg/Week

Product Description

Arbutin 
 
Botanical Source: Arctostaphylos uva-ursi
Part Used: Dried leaf                                                                            
Specification: Arbutin 20%, 10:1 
CAS No.: 497-76-7
Molecular Formula: C₁₂H₁₆O₇                                                                                                                                   
Molecular Weight: 272.25                                                                        
Melting Point: 199~201(±0.5)ºC
optical rotation: [α]D20=-64.00±1.00
                   
Brief Introduction
   Arbutin is a derivative of hydroquinone naturally found in some evergreen plants. As a derivative of hydroquinone, arbutin is banned in dietary aids because of toxicity. However, it is considered a non-phenol alternative to hydroquinone for dermatologic and cosmetic use. In topical applications, arbutin reduces pigmentation in the skin and has been used as a skin-lightening agent since the 1960s. Currently arbutin is combined with other active ingredients in skin-care regimens to treat dark patches from sun exposure, freckles, liver spots and age spots.
Arbutin is a glycoside; a glycosylated hydroquinone extracted from the bearberry plant in the genus Arctostaphylos. It inhibits tyrosinase and thus prevents the formation of melanin. Arbutin is therefore used as a skin-lightening agent. Arbutin is found in wheat, and is concentrated in pear skins. It is also found in Bergenia crassifolia. Arbutin was also produced by an in vitro culture of Schisandra chinensis.
 
Significance
    Arbutin is extracted from the leaves of various types of plants, most notably the bearberry plant (Arctostaphylas uva-ursi), cranberries and blueberries, as well as in wheat and pear skins. Arbutin is converted by the body to hydroquinone, which is a type of phenol with disinfecting and diuretic properties. Arbutin was found in teas, tinctures and capsules as bearberry extracts or uva ursi extracts for weight control and menstruation aids before an FDA ban in 1990. Currently, arbutin is available in topical formulations for skin lightening because of little to no systemic absorption.
 
Function: 
    Arbutin is a glucosulated hydroquinone, extracted from the bearberry plant. Hydroquinone has been commercially available since the 1960s as an agent in skin lightening products.¹ Arbutin is naturally found in wheat, pear skins, and the leaves of blueberries and cranberries, and it is metabolized by the body to produce hydroquinone with most of the product excreted in urine. Topical application of arbutin inhibits the production of melanin with minimal systemic absorption.Arbutin is used as a stabilizer for color photographs, diuretics, anti-infectives for the urinary system, and as a skin-lightening agent. Arbutin has similar effects as hydroquinone, inhibiting melanin formation.
    Bearberry extract is used in skin lightening treatments designed for long term and regular use. An active agent in brands of skin lightening preparations, it is more expensive than traditional skin lightening ingredients like hydroquinone, which is now banned in many countries. In vitro studies of human melanocytes exposed to arbutin at concentrations below 300 μg/mL reported decreased tyrosinase activity and melanin content with little evidence of cytotoxicity.
 
Benefits
    In topical formulations, the effects of arbutin are localized and dose-dependent, which provides control in managing the extent of skin lightening. Products containing arbutin can be used according to the severity of hyperpigmentation, and lower doses and reduced frequency can be employed to fine-tune skin tone. Since arbutin has limited penetration and little to no systemic absorption, use of arbutin-containing products can be stopped to allow normalized skin cells to grow (without overstimulated melanin).
 
Considerations
    Topical use of arbutin is considered to be safe and effective. Since arbutin is included in various skin products, consideration regarding the effects of the other ingredients is recommended. Prolonged use of arbutin may produce uneven pigmentation such as patches of skin with no pigmentation because its effect is localized.
 
Characteristic
- We can also customize orders as customer's requirements and specifications. 
- KINGHERBS' is specialized in manufacturing and exporting different kinds of food industry related goods, such as Artemisinin, Myricetin, Olive Leaf Extract Oleuropein 10%~80%, Hydroxytyrosol 5%-50%; 
Olive Fruit Extract Maslinic Acid 5%~50% ; Dihydromyricetin, Sea Buckthorn Oil,   Zinger Zerumbet Extract
Fenugreek Seed Extract Furostanol Saponins 50%, Apple Root extract, Rosemary Extract Rosmarinic Acid 2%~98%, Carnosic Acid 5%~80% etc
- With the effective exporting system and prompt reaction, we ensure that we can transfer the shipping documents and deliver our cargoes on time. 

FAQ
Q1. About Price: 
The price is negotiable. It can be changed according to your quantity or package. 
Q2. About Sample: 
We can provide the typical size of samples, but the air freight is collect or you pay us the cost in advance.
Q3. About MOQ:
We have no provisions of MOQ, but usually 1KG.
Q4:About Delivery Time
Usually 5-10 days after payment