Milk Thistle Extract
Product Name: Milk Thistle Extract
Botanical Source: Silybum marianum (L.)Gaertn
Plant Part Used: Seed
Specification: Silymarin 80% by UV, Silybin 30% HPLC; Silymarin 80% by UV, Silybin+Isosilybin 30% by HPLC
CAS No.: 22888-70-6
Molecular Formulation: C25H22O10
Molecular Weight: 482.43
| Analysis Items |
Specifications |
| Appearance |
Fine Yellowish Brown Powder |
| Odor & Taste |
Characteristic |
| Bulk Density |
50-60g/100ml |
| Particle Size |
NLT 95% through 80 Mesh |
| Solubility |
Practically insoluble in water, soluble in Methanol & acetone |
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| Assay |
NLT 80% silymarin |
| Silymarin |
| Sum of silycristin and silydianin |
| Sum of silybin А and silybin В |
| Sum of isosilybin А and isosilybin В |
| Loss on Drying |
NMT 5.0% |
| Sulphated Ash |
NMT 0.5% |
| Extract Solvents & Residue |
Acetone NMT 5000ppm |
| Ethanol NMT 5000ppm |
| N-hexane NMT 290ppm |
Indications:
Milk thistle's common name comes from the white markings on the leaves, its milky white sap, and its traditional use by nursing mothers to increase milk. But it is best known for its use as a liver protectant and decongestant, which can be traced to the Greeks and Pliny the Elder (23-79AD), who wrote that it was excellent for "carrying off bile." The famous English herbalist Culpepper (1616-1654) used milk thistle to cleanse the liver and spleen, and to treat jaundice and gallstones.
The whole herb contains flavonoids and fumaric acid; Seeds contain silybin, isosilybin, dehydrosilybin, silydianin, silychristin, silybin polymer and cinnamic acid, myristic acid, palmitoleic acid, arachidonic acid, etc.
1. Liver protection
Silymarin is the main active ingredient of liver protection, which can stimulate the formation of new liver cells and improve liver function. At the same time, it can protect the liver cell membrane, prevent the infiltration of cytotoxin into liver cells, and improve the recovery ability of membrane structure defect.
2. Antioxidant
Silymarin's phenolic hydroxyl group provides hydrogen and has a powerful antioxidant effect. They have the properties of scavenging free radicals and anti-lipid peroxidation activity.
3. Reduce blood lipid
Silybin can inhibit the plasma membrane Ca2+ channel of myocardium in adult rats, inhibit food-induced hypercholesterolemia, decrease very low density lipoprotein (VLDL) and low density lipoprotein (LDL), and increase high density lipoprotein (HDL), which can be used for the treatment of cardiovascular diseases.
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