Phellodendron Amurense Bark Extract
Product Name: Phellodendron Amurense Bark Extract
Latin Name: Cortex Phellodendri Chinensis
CAS No.: 164288-52-2
Part Used: Bark
Appearance: Fine light yellow powder
Active Ingredient Markers: 97% Berberine Hydrochloride
Ingredients of Phellodendri Amurense Powder:
Berberine[C20H18NO4]+(0.63%~5.91%)
palmatine[C21H22NO4]+(0.372%~0.590%),
jatrorrhizine[C20H20NO4]+(0.028%),
phellodendrine [C20H24NO4]+,menisperine,candicine,obacunone,etc
Charcteristic
It is well known that Amur cork tree, or called phellodendron amurense in scientific name and Huang Bo in mandarin, is partly grown for the purpose as timber, which is the preferred type of wood for building houses and making high-end furniture because it comes with moderate hardness, graceful wood grain, and strong corrosion-resistance properties. Similarly, this plant, especially its bark, is also an equally remarkable Chinese herb thanks to its strong anti-inflammatory effect. As a matter of fact, it is a must-have ingredient in all kinds of traditional Chinese medicine pills. Unfortunately, in recent years the growing role of its medicinal value results in excessive illegal logging and the diminishing Amur corktree resources. So, in this case it needs to avoid abusing this herb. And as herbalists, what we can and should do is to better understand and make better use this herb medicinally.
Chinese Amur cork tree bark benefits
This herb was first found in "Shen Nong's Herbal Classic", in which it was listed as the highest grade and classified into the group of heat-clearing and damp-drying drug. The best medicinal quality usually comes from those phellodendron that is about 10 year old. Unfortunately the tree will die soon after it is peeled. As a result, it is also one of rare and valuable Chinese herbs. Clinically it is usually used for the treatment of cerebrospinal meningitis, bacillary dysentery, pneumonia, tuberculosis, liver cirrhosis, chronic hepatitis, trichomoniasis vaginitis, acute conjunctivitis, chronic suppurative otitis media, cervical spondylosis, ear eczema, and more. And its pharmacology seems have more related information and evidence.
Amur corktree bark side effects and contraindications
The safety of Amur corktree bark is also a major concern. And it was rated with a class 2B by the AHPA. That's to say, it should be avoided in pregnant women. And it is reported that overdose of this herb may lead to vomiting and nausea. According to Ben Cao Jing Ji Zhu (Explanation of Canon of Materia Medica), it contradicts Gan Qi (Resina Toxicodendri). Besides, it shouldn't be used in the cases of diarrhea caused by spleen deficiency and deficiency-cold in spleen and stomach.
Function
1.Being as diuretic and cooling herb that stimulates the liver and gall bladder. It has been used traditionally to lower fever and to reduce blood pressure and blood sugar levels;
2.Having a strong antibacterial effect and being used internally to treat diarrhea, dysentery, enteritis, vaginal infections, acute urinary tract infections, abscesses, tumors, jaundice, night sweats and skin diseases;
3.Phellodendron bark is bitter in taste and cold in action. Reducing inflammation and dampness, 4.Anti-bacterial and anti-viral activity;
5 To eliminate any disease characterized by hectic fever.
| Identification |
Both spectra exhibit similar intensities of absorption at the same wavelengths. |
Conforms |
UV |
| Compare the spectrum with the Reference Spectrum, both spectra exhibit similar intensitites of absorption at the same wavelengths |
Conforms |
IR |
| Chemical reaction |
Conforms |
Chemical reaction |
| Appearance |
Fine Yellow Crystal Powder |
Conforms |
Visual test |
| Odor & Taste |
Characteristic, strong bitter, odorless |
Conforms |
Organoleptic test |
| Bulk Density |
40-55g/100ml |
Conforms |
ASTM D1895B |
| Particle Size |
98% through 80 mesh |
Conforms |
AOAC 973.03 |
| Solubility |
It is spaingly soluble in methanol, slightly soluble in ethanol (95), and very slightly solubal in water |
Conforms |
Visual |
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| Assay |
Berberine HCL 98%-102% |
99.0% |
Titration |
| Acidity |
The yellow colr changes to an orange to red color |
Conforms |
/ |
| Loss on Drying |
NMT 12.0% |
10.50% |
JP17 |
| Sulfated ash |
NMT 0.1% |
Conforms |
JP17 |
| Extract Solvents |
Ethanol |
Conforms |
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| Heavy Metals |
NMT 30ppm |
NMT 10ppm |
JP17 |
| Sulfate |
NMT 0.048% |
Conforms |
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| 666 |
NMT 0.1ppm |
Conforms |
GC |
| DDT |
NMT 0.5ppm |
Conforms |
GC |
| Acephate |
NMT 0.2ppm |
Conforms |
GC |
| Methamidophos |
NMT 0.2ppm |
Conforms |
GC |
| Parathion-ethyl |
NMT 0.2ppm |
Conforms |
GC |
| PCNB |
NMT 0.1ppm |
Conforms |
GC |
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| Sterilization Method |
High temperature & pressure for a short time of 5~10 seconds |
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| Microbiological Data |
Total Plate Count<10,000cfu/g |
<1,000cfu/g |
GB 4789.2 |
| Total Yeast & Mold<1,000cfu/g |
< 100 cfu/g |
GB 4789.15 |
| E. Coli to be absent |
Absent |
GB 4789.3 |
| Staphylococcus to be absent |
Absent |
GB 4789.10 |
| Salmonella to be absent |
Absent |
GB 4789.4 |
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| Packing and Storage |
Packed in fiber drum, LDPE bag inside. Net weight: 25kgs/drum. |
| Keep well sealed, away from moisture, strong heat and sunlight. |
| Shelf Life |
1 year if sealed and stored in the recommended conditions. |
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