100% Natural Milk Thistle Extract for Protecting Liver

• Certification: ISO, FDA, HACCP, Kosher,Halal
• Assay Method: HPLC, UV
• Application Form: Tablet, Capsule
• Application: Food, Health Care Products
• State: Powder
• Extract Source: Silybum Marianum (L.) Gaertn
• Model NO.: 40%-80% Silymarin
• Appearance: Fine Yellow to Yellowish Brown Powder
• Loss on Drying: Nmt 5.0%
• Sulphated Ash: Nmt 0.5%
• Transport Package: 25kgs/Drum
• Specification: 40%-80% Silymarin
• Origin: China
• HS Code: 2938909090
• Production Capacity: 5000kg

Product Description

Milk Thistle Extract

Specification: 40%-80% Silymarin
Botanical Source: Silybum Marianum (L.) Gaertn
Plant Part Used: Seed,100% Natural
Active Ingredient Markers: Silymarin, Silybins

Introduction:
The greatest contribution of silymarin is to stabilize the liver cell membrane, which prevents or avoids the loss of lytic cellular components such as transaminases. Silymarin can limit the penetration of certain hepatotoxic substances (such as alpha-amanitamin) into the cell interior. The enhancement of protein synthesis capacity is due to silymarin stimulating the activity of RNA polymerase I in the nucleus, thus assisting the synthesis of ribosomal RNA in hepatocytes, resulting in the massive synthesis of structural and functional proteins (enzymes). Therefore, silymarin can enhance the repair and regeneration capacity of liver cells.
 

Analysis Items		Specifications	Results		Methods used
Appearance		Fine Yellow to Yellowish Brown Powder	Conforms		Visual test
Odor & Taste		Characteristic	Conforms		Organoleptic test
Bulk Density		50-60g/100ml	Conforms		ASTM D1895B
Particle Size		NLT 98% through 80 Mesh	Conforms		AOAC 973.03
Solubility		Practically insoluble in water, soluble in Methanol & acetone	Conforms		Visual
Assay		NLT 80% silymarin	80.14%		UV
		Silymarin	33.39%		HPLC
		Sum of silycristin and silydianin	16.05%		HPLC
		Sum of silybin А and silybin В	10.87%		HPLC
		Sum of isosilybin А and isosilybin В	6.47%		HPLC
Loss on Drying		NMT 5.0%	2.33%		5g /105ºC /2hrs
Sulphated Ash		NMT 0.5%	0.29%		2g /525ºC /3hrs
Extract Solvents & Residue		Acetone NMT 5000ppm	33.29ppm		USP 34
		Ethanol  NMT 5000ppm	2781ppm		USP 34
		N-hexane  NMT 290ppm	0.19ppm		USP 34
Heavy Metals		NMT 10ppm	Conforms		ICP-MS
Arsenic (As)		NMT 1ppm	0.064ppm		ICP-MS
Lead (Pb)		NMT 3ppm	0.022ppm		ICP-MS
Cadmium (Cd)		NMT 1ppm	0.001ppm		ICP-MS
Mercury (Hg)		NMT 0.1ppm	0.001ppm		ICP-MS

Benefit:
1. Remove reactive oxygen species
2. Hepatoprotective effect
3. Anti-tumor effect
4. Anti-cardiovascular disease
5. Protective effect of cerebral ischemia injury